The aim of this module is t o provide the student with an overview of the drug discovery and development process and the pathway to regulatory approval for safe and effective medicines . The module will cover the theoretical background to drug development in lectures with application of knowledge via hands-on computer molecular modelling classes and integrative problem-solving and decision-making workshops.

1. Describe the overall drug discovery and development process and the current challenges faced
2. Discuss the different sources of drugs and the methods used for drug discovery and design and structure elucidation
3. Explain how drug targets are identified and validated
4. Recall medicinal chemistry concepts, functional group chemistry, structure activity relationships and drug physicochemical properties in relation to disease drug targets
5. Discuss the properties that make a good drug molecule
6. Demonstrate knowledge of preclinical pharmacology and toxicology principles and the studies needed prior to human exposure of a new drug molecule
7. Outline the regulatory aspects of drug development including clinical studies and the pathway to new drug approval
8. Explain processes for ensuring quality, efficacy and safety of drugs on the market

This module will describe the theory of natural sources of medicines and the techniques used in pharmacognosy. Students will be introduced to the use of complementary, traditional and alternative medicines. Standardisation, quality control and legislation will be discussed in relation to herbal medicines . Hands-on practical classes will provide students with the opportunity to apply their theoretical pharmacognosy knowledge to the isolation and evaluation of natural compounds.

1. Outline the evolution of the use of natural products in drug discovery, sources of natural products and traditional uses and their contribution to modern medicine
2. Show basic knowledge of biosynthesis by plants and fungi, the use of secondary metabolites as drug molecules and the major phytochemical groups with known biological activity and medicinal uses
3. Demonstrate skills in and knowledge of the different methods used for the classification and identification of natural compounds
4. Describe the different techniques used for the isolation, extraction, purification, identification and screening for biological activity of natural compounds and demonstrate practical ability
5. Demonstrate knowledge of cosmeceuticals, their uses and key examples. Discuss scientific and clinical evidence
6. Define the term complementary and alternative medicine (CAM) and discuss the origin, theory, practice and beliefs associated with the different types of CAMs
7. Understand the role that CAMs and traditional medicines play in healthcare, public health, health promotion, patient choice and empowerment
8. Assess the use of CAMs in terms of clinical uses, scientific and clinical evidence-based use, efficiacy , toxicity, drug interactions. Describe the risks of alternative therapies and understand the role of the pharmacist in CAMs provision and patient education
9. Show awareness of quality control and regulatory aspects of CAMs and the challenges faced regarding standardisation, efficacy and safety of herbal preparations and natural medicinal products for patient use

The aim of this module is to provide the student with theoretical knowledge of the pharmacology and clinical therapeutics relevant to pharmaceutical drugs used for GI, endocrine and skin conditions and in reproductive health . The major drug classes will be studied and the role of the pharmacist in the management of conditions related to these organ systems will be discussed.

1. Describe the anatomy, physiology and function of the gastrointestinal system, liver, endocrine and reproductive systems and the skin
2. Demonstrate knowledge of the epidemiology, aetiology, pathophysiology, clinical features, diagnosis, complications and progression of common gastrointestinal and liver diseases
3. Outline the therapeutic management of common GI conditions and diseases including self-care and OTC drugs , the medicinal chemistry of common drug classes and their mechanisms of action, formulation, delivery, efficacy and side-effects
4. Discuss the management of liver disorders and therapeutic options in line with patient factors and national guidelines
5. Demonstrate knowledge of endocrine disorders – aetiology, epidemiology, pathophysiology, diagnosis and clinical therapeutic guidelines for the management of endocrine disorders
6. Discuss drug classes used to treat endocrine disorders – mechanism of action, medicinal chemistry, formulation and delivery, adverse effects and therapeutic monitoring
7. Understand the importance of hormone balance to overall patient health
8. Show understanding of reproductive health in men and women and the use of steroid hormones as contraceptives
9. Demonstrate knowledge of the most common skin conditions – aetiology, pathophysiology, signs, symptoms and diagnosis and the distinguishing features of different conditions
10. Distinguish between minor and major skin conditions and advise patients appropriately, particularly concerning referral to other healthcare professionals and available OTC treatments
11. Outline the mechanisms of action, medicinal chemistry, formulation, drug delivery and pharmacokinetics for the major drug classes used for the treatment of skin conditions

This module develops the students' ability and competence in clinical skills and furthers understanding in practice-related ethics and legislation. Students will gain knowledge and experience in responding to symptoms and demonstrating clinical skills in a wide range of health and disease states including stoma appliances, childhood conditions, travel health and skin conditions. Laboratory test results and therapeutic monitoring will be covered in detail.

Students will undertake two weeks of practice placement in the second semester. Students will complete HSeLanD Communicating Effectively through Open Disclosure training prior to practice placement.

1. Recognise symptoms of a wider range of common illnesses and suggest appropriate management
2. Discuss symptoms and management of common conditions in special patient groups such as children, those with co-morbidities and in pregnancy
3. Review more complex prescriptions to determine clinical appropriateness both for the patient and disease and assess choice of formulation, dose and potential interactions or contraindications and adverse effects
4. Demonstrate further development of communication skills and the competency to gather relevant patient information for more complex patient case studies relevant to year 2 clinical therapeutics modules and interpret knowledge on their condition and medicines appropriately and accurately to provide patient counselling and recommendations and for the development of pharmaceutical care plans
5. Practice accurate and safe dispensing skills and preparation of medicines for more complex prescriptions in accordance with legal and professional requirements
6. Apply knowledge of ethical and professional obligations of the pharmacist in accordance with statutory codes of conduct including continuing professional development and fitness to practice requirements
7. Discuss the legal requirements, regulations and processes governing the supply of medicines and control of pharmacy practice in Ireland
8. Explain risk minimisation procedures relevant to pharmacies and the supply of medicines. Follow quality and risk management practices and record and maintain appropriate records
9. Describe public and global health initiatives and campaigns in relation to clinical conditions studied in other modules in second year and actively engage in discussion in promotion of health
10. Define the role of the pharmacist in travel health and discuss common travel health risks, conditions, prophylaxis and treatments
11. Know and discuss the regulations surrounding the supply of veterinary medicines
12. Show further development of skills in pharmaceutical calculations, problem-solving patient case studies and presentation skills
13. Demonstrate continuing professional and personal development, self-reflective practice and creation of self-learning plans and document accordingly in CPD portfolio
14. Discuss the importance of and demonstrate ability to build professional relationships, communicate with non-pharmacy professionals and participate in interprofessional team discussions to improve patient outcome
15.
Outline the importance of peer review in the context of literature and critically discuss evidence-based practice and apply knowledge to justify treatment recommendations

This module will cover the pharmacology and clinical therapeutics of pharmaceutical products and medicines used in circulatory, cardiovascular and renal conditions . Students will gain theoretical knowledge of diseases and conditions common to these organ systems. Th e module will also discuss the national and international guidelines for therapeutic management of these conditions, disease biomarker s, common drug classe s and associated therapeutic monitoring.

1. Describe the physiology and function of the cardiovascular and renal systems
2. Demonstrate knowledge of the epidemiology, aetiology, risk factors , patholog y, signs and symptoms of cardiovascular and renal disease and show awareness of the global impact and the role of the pharmacist particularly with regards to patient factors, health promotion and public health
3. Outline the common drug classes used in the therapeutic management of cardiovascular and renal disease, their mechanisms of action, medicinal chemistry, physicochemical properties and use of appropriate formulations and delivery
4. Summ arise the different types of anaemia, their pathophysiology and therapeutic management and relationship between anaemia and cardiovascular and renal disease
5. Describe the diagnostic tools and criteria used for diagnosis and progression of cardiovascular and renal diseases and discuss the international guidelines and evidence-based practice for their clinical therapeutic management
6. Outline the mechanisms of haemostasis and the development of thrombotic disorders and d emonstrate knowledge of drugs used for the treatment of thrombosis and haemostasis, their mechanisms of action, medicinal chemistry, formulation and drug delivery
7. Explain the importance of therapeutic monitoring and the measurement of biomarkers in the therapeutic management of cardiovascular and renal disease and thrombotic disorders

The aim of this module is t o further develop theoretical understanding of the physicochemical properties of drug molecules and the characteristics important for dosage form design. The module will also describe basic pharmacokinetics principles, inter-individual variability and the impact of this on medicines use . Practical laboratory classes will introduce the student to product testing and pharmacokinetic simulation.

1. Explain the importance of solid-state characterisation for the preparation of pharmaceutical products
2. Demonstrate knowledge of different solid – state forms and the compatibility between drug molecules and excipients in solid dosage forms
3. Describe physicochemical properties important for the formulation and manufacture of solid dosage forms and the relationship with stability, degradation and route of administration
4. Apply knowledge of the basic principles of pharmacokinetics in the use of pharmacokinetic models and equations
5. Discuss factors that can lead to pharmacokinetic variability and how these can affect efficacy and safety and dosage regimens
6. Describe the use of the Biopharmaceutical Classification System (BCS system) as a tool in the formulation development and design of drugs

This module will provide a continuation of formulation sciences and explore the formulation of further dosage forms. An introduction to the technologies used in the production of medicines will be given. Theoretical knowledge gained in lectures will be applied in hand-on laboratory practical classes. Workshops will facilitate integrative problem-solving and decision-making skills in formulation science.

1. Discuss the design, formulation and production of oral solid dose formulations in relation to the physicochemical properties of drug molecules, pharmacokinetics and the patient
2. Perform appropriate pharmaceutical calculations to design, formulate and compound solid dosage forms
3. Demonstrate knowledge of powder technology and the importance of particle size and powder flow, mixing, compressibility in solid dose formulation
4. Differentiate between immediate, modified and controlled release oral and transdermal formulations and explain their relevance to patient care
5. Outline the development and formulation of other dosage forms including rectal, vaginal and inhalation and relate to drug properties, patient factors and disease
6. Discuss packaging materials with consideration to person-centred care and key packaging technologies
7. Describe tablet manufacturing, powder sizing, mixing, granulation, compression, coating and encapsulation technologies and its impact on product quality and stability.
8. Show basic awareness of quality by design, process analytical technology and methods used for solid state characterisation, analysis and quality control including CQAs and KPPs
9. Demonstrate competency in pharmaceutics laboratory skills and formulation calculations and an understanding of GMP and GLP in relation to a medicinal product QMS.

This module will provide the student with theoretical background on the pharmacology and clinical therapeutics of medicines used in CNS disorders. The module will provide an overview of drugs used in pain and anaesthesia. The challenges with CNS drug development will be discussed and the student will be introduced to the concepts of dependency and addiction.

1. Describe the anatomy and physiology of the central nervous system and o utline the pathophysiology, neurobiological pathways and neurochemistry involved in common CNS disorders
2. Discuss clinical therapeutics for common CNS and mental health disorders and understand the mechanism of action of drug classes in relation to receptor pharmacology, neurochemistry, medicinal chemistry, pharmacokinetics, adverse effects, toxicology and neurobiological adaptation
3.
Assess appropriate drug therapy in relation to national and international patient guidelines for neurological, psychiatric and neurodegenerative disorders

4. Understand the clinical pharmacology of local and general anaesthetic drugs and d escribe the different pain pathways and the drug classes used in pain management
5. Show awareness of the challenges faced in CNS drug discovery and delivery and the treatment of patients. Possess basic knowledge of current CNS therapy research areas and drug development
6. Explain basic concepts of drug tolerance, dependency and addiction

The aim of this module is t o provide the student with an overview of the pharmacology and clinical therapeutics of drugs used in the treatment of the most common cancers. An introduction to t he immune system and immunomodulators will be covere d. The module will include discussion on vaccination strategies and oncology therapy guidelines

1. Outline the epidemiology, signs, symptoms and multifactorial causes of the most frequent cancers as well as preventative strategies
2. Understand the cell biology and biochemical processes that lead to tumour cell development, growth, conversion to malignancy and progression
3. Discuss the standard treatment options for the most frequent cancers in line with national and international guidelines, responsiveness to treatment, outcomes and survival rates
4. Demonstrate knowledge of the main classes of anticancer agents and chemotherapy associated drugs – medicinal chemistry, mechanisms of action, formulation, route of administration, dosing regimens, pharmacokinetics, toxicities and mechanisms of toxicity
5. Understand the challenges faced in cancer therapy including drug resistance, patient-related factors, toxicities and the typical approaches taken including treatment combinations and options to minimise side-effects
6. Show competency in performing chemotherapy dose and dosing schedule calculations. Discuss the formulation, production, reconstitution and dispensing of chemotherapy doses and handling of cytotoxic compounds
7. Discuss the role of the pharmacist within the wider care plan for a patient with cancer
8. Describe the physiology and function of the different cells and organs of the human immune system and explain innate immunity, the complement system, B cells, T cells, antigens and antibodies and their roles
9. Demonstrate knowledge of abnormal function and diseases of the immune system including hypersensitivity, allergic reactions, autoimmune diseases and syndromes, immunodeficiencies – mechanisms and pathways involved and the impact on patient health and response to infection
10. Outline drug therapies used to modulate the immune system including immunosuppression and vaccination

This module will enable students to continue to develop their knowledge of pharmacy practice and the related professional, ethical and legal aspects. Communication and patient counselling skills, medicines use reviews, clinical skills, critical review, professional decision-making and peer review skills will be advanced. The module will also cover topics such as misuse of drugs, family planning, veterinary pharmacy, research skills for pharmacists and career planning .

1. Demonstrate continued development of professional pharmacy skills in situations with increasing complexity
2. Discuss the legislation and ethical and professional requirements of a pharmacist in relation to advanced practice
3. Show confidence in communicating with patients – use effective and empathetic questioning and active listening skills to collect and interpret information about the patient, their health and medicines. Demonstrate appropriate patient counselling skills in more complex cases and provide and justify recommendations
4. Integrate clinical therapeutics knowledge to accurately check and dispense increasingly complex prescriptions, in line with legal and ethical requirements, to determine and justify clinical appropriateness of prescribed medicines and suggest changes if needed
5. Effectively conduct medicines use reviews relevant to selected clinical therapeutics modules and communicate appropriately with patients to improve health and disease management
6. Explain the importance of safe medicines supply and use. Discuss risk management processes and implement appropriate practices to minimise risk, maintain quality management systems, identify and report errors and accurately maintain records
7. Apply professional communication skills, solve ethical dilemmas, make professional judgements and decisions and work collaboratively with other healthcare professionals to ensure appropriate patient-centred care
8. Discuss the pharmacology, formulation, administration and clinical use of selected veterinary products
9. Demonstrate networking skills, build professional relationships and interact within pharmacy practice and interprofessional teams. Understand the roles of other health professionals and the need to work effectively and professionally in multidisciplinary teams for best practice and improved patient outcome
10. Perform peer review and critical assessment and provide feedback to team members. Demonstrate leadership and management skills
11. Critically evaluate and review information sources to assess clinical effectiveness of medicines and make an informed opinion based on evidence-based options available
12. Discuss risk:benefit analysis of medication and demonstrate ethical decision-making skills
13. Demonstrate continuing professional and personal development and self-reflective practice and independent learning and development skills in line with relevant codes of conduct for pharmacy students. Document personal and professional development in CPD portfolio
14. Demonstrate competency in performing advanced pharmaceutical calculations

The aim of this module is to provide the student with theoretical knowledge and understanding of the role of the pharmacist in public and population health. This module will discuss current public and population health issues, healthcare services and national strategies as well barriers to healthcare and health economics . A focus of the module will be on overcoming barriers, challenges and ethical dilemmas

1. Describe national and global public and population health issues and discuss the burden on health care and health governance, health policies and strategies, health screening, health promotion and the role of the pharmacist
2. Explain epidemiology and health economics concepts and their use in determining current and future trends in national and global health and healthcare
3. Understand the role of social and behavioural sciences in health, illness and the practice of pharmacy and apply the principles to improve health
4. Discuss the misuse of drugs and addiction in Ireland and globally and understand the role of the pharmacist in drug and substance misuse
5. Critically analyse human rights, ethics and health inequalities in relation to population and public health, health screening, provision of health services and health promotion
6. Discuss gender-related and person-specific factors including disability influencing health, health-care needs, illness, wellbeing, accessing health services and response to medication and understand how to address such barriers and tailor solutions
7. Demonstrate an awareness of barriers preventing access to healthcare in minority groups and LGBTQIA+ communities and the role of pharmacist in facilitating and supporting access
8. Show understanding of children’s health, childhood vaccination, illnesses and paediatric prescribing in relation to pharmacy practice
9. Demonstrate knowledge of sexual health, sexual health-related issues, sexual health services and sexual health promotion strategies
10. Outline the most common age-related diseases in the elderly and patient-centred healthcare and discuss the role of the pharmacist in the care of the elderly
11. Apply knowledge of health policies and services available to make professional and ethical decisions and suggestions for best practice and patient-centred care

T his module will provide the student with theoretical knowledge on the pharmacology and clinical therapeutics of drugs used in the treatment of respiratory, musculoskeletal, inflammatory and ocular conditions. The inflammatory response and therapeutic use of corticosteroids will be covered . The module will discuss the therapeutic approaches in line with national and international guidelines.

1. Outline the aetiology, epidemiology and pathophysiology of common respiratory diseases and musculoskeletal disorders, their symptoms, diagnostic tests and diagnostic criteria
2. Discuss the medicinal chemistry, mechanism of action, formulation, physicochemical properties and delivery of different drug classes used for the treatment of respiratory and musculoskeletal conditions
3. Explain the formulation, production and use of inhalation drugs in terms of efficacy, safety, pharmacokinetics and patient use and benefit
4. Understand the therapeutic approaches taken for the management of respiratory diseases and musculoskeletal disorders in line with national and international guidelines and appropriate to the individual patient
5. Review patient clinical and medical history and create pharmaceutical care plans for respiratory and musculoskeletal diseases, outline the importance of adherence to medication used for respiratory and musculoskeletal systems and advise patients on use of medications
6. Describe the cascade of events that occur in the inflammatory response and discuss the role it plays in host defence
7. Discuss anti-inflammatory drug classes, their mechanisms of action, clinical uses, side-effects, cautions and choice of drug relative to different patient groups and diseases
8. Demonstrate knowledge of the structure, physiology and function of the eye in healthy and disease states and the aetiology, pathophysiology, signs, symptoms and diagnosis of the most common eye conditions
9. Distinguish between minor and major eye conditions and advise patients appropriately, particularly concerning referral to other healthcare professionals and available OTC treatments
10. Outline the mechanisms of action, medicinal chemistry, formulation and drug delivery for the major drug classes used for the treatment of eye conditions and understand the scientific and clinical rationale for their use in accordance with national guidelines

This module will provide a theoretical overview of sterile product manufacturing and radiopharmaceuticals and introduce quality systems. The importance of sterile product manufacture will be considered. Students will gain hands-on experience in sterile product compounding. An introduction to biopharmaceutials will be given with discussion on the production and regulatory aspects of biotechnology produced pharmaceuticals .

1. Explain the importance of sterile product manufacturing for particular classes of pharmaceutical products in relation to the route of administration, the patient and disease
2. Outline the risks of contamination and methods of sterilisation for different types of microorganisms that pose a problem in pharmaceutical products
3. Discuss the principles of pharmaceutical clean room design, aseptic manufacturing, unit operations, quality control, quality assurance, acceptable limits, Good Manufacturing Practice, validation and process monitoring
4. Describe and appraise the design, formulation, manufacture, packaging and labelling of sterile pharmaceutical products
5. Perform pharmaceutical calculations, select appropriate excipients , packaging and labelling and aseptically prepare sterile products
6. Outline the development, production and clinical use of radiopharmaceuticals and radiopharmaceutical dosage forms
7. Recall the different classes of biotechnology produced pharmaceutical products and demonstrate knowledge of their clinical uses, mode of action, formulation, production, delivery and pharmacokinetics
8. Discuss the stability, purity, formulation and dosage forms of biopharmaceuticals and any challenges and safety concerns
9. Differentiate the regulatory requirements and pathways associated with biopharmaceuticals from those for small molecular entities
10. Develop an understanding of the high cost associated with certain biotechnology produced pharmaceutical products and discuss in context of the disease, therapeutic efficacy, patient/payer and patient challenges and outcomes

This module will provide the student with an overview on recent approvals in the biologics field and increase theoretical knowledge on individualised therapies and companion diagnostics . The module will familiarise the student with advanced therapies medicinal products and orphan drugs, and the development and regulatory pathways for these therapeutics . A key theme in this module will be the challenges associated with the development of advanced therapeutic products

1. Evaluate recently approved biologics in terms of clinical indications, pharmacology and advancements in formulation and delivery
2. Demonstrate knowledge of the late drug development pipeline and future therapeutic trends for biopharmaceuticals
3. Discuss the importance and use of stratified and personalised medicines. Understand the application of pharmacogenomics, biomarker measurement and companion diagnostics and the pharmaceutical development of personalised medicines and companion diagnostics
4. Define orphan diseases and using examples discuss the development and therapeutic use of orphan drugs from a patient, pharmaceutical company, health service, payer, and regulatory perspective
5. Outline the current and emerging Advanced Therapy Medicinal Products (ATMPs), their different classes, formulation, production, delivery, clinical uses, clinical pharmacology
6. Critically discuss the challenges and limitations surrounding Advanced Therapy Investigational Medicinal Products (ATIMPS) – particularly clinical trials and regulatory implications
7.
Describe advancements in cancer drug development and recently approved oncology therapies, their formulation, delivery, clinical uses, efficiency and side-effect profiles

8. Discuss the current therapies for diseases with unmet clinical need such as CNS disorders and rare diseases
9. Critically discuss the clinical use of unlicensed medicines and drug repurposing to meet current clinical needs and the regulatory implications

Th e aim of this module is to provide an opportunity for students to stay up to date with theoretical knowledge on innovation in pharmaceutical formulation and the current challenges in formulation and drug delivery. The module will outline an overview on advanced drug delivery systems and medical devices . Students will critically evaluate research in the field

1. Understand and critically assess the need for continuous innovation in pharmaceutical formulation and drug delivery systems for effective and safe patient-centred care
2. Describe the challenges faced in the formulation and delivery of both small and large molecules and the pharmaceutical strategies taken to increase drug duration of action, reduce rate of elimination or enhance delivery to meet therapeutic needs
3. Discuss novel and updated formulations and delivery systems in terms of clinical need, efficacy, safety, physicochemical properties of drugs, individual patient groups and patient compliance
4. Describe and discuss advanced drug delivery devices with examples, their clinical uses, formulation or technology used, their advantages and disadvantages
5. Outline the development of generic drugs and biosimilars and understand the concepts of bioequivalence, pharmaceutical equivalence and therapeutic equivalence and their importance from a global health and economic perspective
6. Explain the classification of medical devices and the devices current available and used clinically. Demonstrate understanding of the manufacturing of medical devices and regulatory guidelines for development and use
7. Critically analyse research articles and articulate evidence-based opinion on advancements in formulation and delivery systems

This module will allow the student to develop professional practice skills from Domain 2 of the Core Competency Framework (CCF) for Pharmacists . The module will focus on a pplying a ‘person-centred’ approach, practising legally and ethically, the commitment to lifelong learning and development, adapting to change and innovation, and the commitment to evidence-based practice. The module will be delivered online as directed learning, and it will be managed aligned to the APPEL structures (Affiliation for Pharmacy Practice Experiential Learning), in common with other MPharm programmes. This module will be undertaken while on four months (30 hr per week) of work placement and the student will have the opportunity to use their professional practice skills. Developing competence in domains 1,2 and 3 of the Core Competency Framework (CCF) for Pharmacists will be of particular emphasis during this practice placement.

100 % attendance is required for practice placement.

1. Participate in accordance with the behaviours outlined in Domain 2 of the Core Competency Framework
2. Describe the legal requirements regulating pharmacy practice and demonstrate competency in professional practice according to Irish and European legislation
3. Discuss the ethical codes of conduct applicable to pharmacists and professional behaviour
4. Recognise, critically review and take action to resolve ethical dilemmas in practice
5. Take responsibility and integrate knowledge and skills to ensure safe and effective practice for medicines use, supply and distribution
6. Understand the importance of a person-centred approach and practice accordingly to ensure best patient outcomes
7. Apply evidence-based practice, cost-effective guidelines and knowledge to justify professional decisions
8. Demonstrate continuing personal and professional reflective practice, learning and development with documented evidence
9. Discuss future professional pharmacy roles and innovation in pharmacy practice and healthcare. Show adaptability to change and innovation
10. Understand the need for digital competence and engage with innovation for best practice

This module will allow the student to develop professional skills, in particular those from Domain 1 of the Core Competency Framework (CCF) for Pharmacists, including leadership, decision-making and problem-solving, collaborative work, and communication skills.
The module will be delivered online as directed learning, and it will be managed aligned to the APPEL structures (Affiliation for Pharmacy Practice Experiential Learning), in common with other MPharm programmes. This module will be undertaken while on four months of work placement (30 hr per week) where the student will have the opportunity to use their professional skills. 100% attendance is required for practice placement

1. Demonstrate competency and practice in accordance with the behaviours outlined in Domain 1 of the Core Competency Framework
2. Exhibit leadership skills, appraise, peer review and provide feedback to others. Safely delegate when appropriate
3. Apply professional and ethical judgement to make informed decisions and justify decisions based on evidence, risk:benefit, ethical and legal requirements and document decisions, when appropriate
4. Apply integrated clinical therapeutics knowledge and skills for effective and safe practice
5. Collaborate and communicate with other healthcare professionals to ensure continuous effective and safe patient-centred care
6. Communicate with others in an appropriate, respectable, sensitive and non-judgemental way displaying skills of both self and social awareness and abiility to tailor communication according to the situation
7. Contribute to peer learning and development and show confidence in appraising roles and responsibilites of other professionals
8. Develop, implement and work within pharmaceutical care plans
9. Demonstrate continued professional and personal learning and development and critical self-reflective practice in line with relevant codes of conduct for pharmacists
10. Demonstrate a systematic approach to learning and practice

This module will allow the student to develop organisation and management skills, in particular those from Domain 3 of the Core Competency Framework (CCF) for Pharmacists, including the ability to manage themselves and the workplace, to manage resources and finance, and have the ability to contribute to continuous quality improvement and risk management.

The module will be delivered online as directed learning, and it will be managed aligned to the APPEL structures (Affiliation for Pharmacy Practice Experiential Learning), in common with other MPharm programmes.

This module will be undertaken while on four months of work placement (30 hr per week) and the student will have the opportunity to use their organisational and management skills.

100% attendance is required for practice placement

1. Demonstrate all competencies included in Domain 3 of the Core Competency Framework
2. Develop, implement and work within standard operating procedures and policies
3. Utilise quality management systems, policies and procedures and integrated with knowledge and skills to ensure safe and effective practice
4. Understand and explain the importance of mentoring, coaching, performance management and leadership and participate in systems and procedures in place within the workplace
5. Discuss the concepts and application of organisational behaviour and change management relevant to the pharmacist
6. Show ability to manage resources within the workplace. Demonstrate skills in financial management and procurement
7. Apply the principles of pharmacoeconomic assessment and cost benefits analyses in decision-making
8. Recognise personal responsibility and apply frameworks for risk management when responding to health and safety matters including critical incidents to mitigate risk to colleagues, patients and the public

This module will enable the student to carry out an individual research project that may be laboratory-based, or literature/data based including literature review, systematic review, meta-analysis. Projects may be related to pharmacy practice, clinical pharmacy, pharmaceutical sciences or in a field related to a previously studied module. Students will gain experience in research skills from formulating a research question to methodology development, data collection and analysis and dissertation writing

1. Apply research skills to conduct an independent research project and demonstrate understanding of the background to the research area
2. Formulate a research question or hypothesis and demonstrate understanding of suitable methodologies for the project
3. Understand and apply ethical research principles, peer review and impact factor when searching the literature and selecting relevant studies for critical review
4. Generate data. Analyse, interpret, critically evaluate and present data accurately and impartially. Use statistical analysis where appropriate
5. Construct appropriate , logical and structured arguments to address research questions or hypotheses with reference to current research and knowledge
6.
Prepare a written research dissertation and oral/poster presentation of research findings

7. Demonstrate research time management skills and presentation skills

This module will provide a theoretical overview of pharmaceutical manufacturing , quality processes and regulatory guidelines. S tudents will gain an understanding of the different roles for pharmacists within the pharmaceutical industry , including Qualified Persons . The module will also outline drug life cycle management, inte lle ctual property , commercialisation and an understanding of pharmaceutical project management.

1. Outline the different roles of the pharmacist in the pharmaceutical industry
2. Systematically describe the processes of pharmaceutical development, manufacturing, packaging and marketing and discuss issues that may arise
3. Demonstrate understanding of analytical tools used to assess the physicochemical properties and quality of raw materials, mixtures and final pharmaceutical products
4. Explain the principles of quality assurance (QA), quality control (QC), good laboratory practice (GLP), good manufacturing practice (GMP) and quality risk management
5.
Demonstrate knowledge of regulatory guidelines and requirements governing the safe manufacture, production and release of pharmaceutical products to the market and understand the processes of documentation, product registration, risk assessment and auditing

6. Describe the role and responsibilities of a Qualified Persons (QP)
7. Discuss drug life cycle management strategies used by the pharma industry and identify possible strategies to increase commercial potential of a drug, meet unmet clinical needs and extend market exclusivity periods
8. Understand the importance of intellectual property rights and patent protection within the pharmaceutical industry
9. Demonstrate understanding of pharmaceutical project management and the different stages

This module will develop skills in the critical appraisal of scientific research and the application of evidence-based knowledge for best practice. The principles of Pharmacoeconomics and the use of pharmacoeconomic modelling to develop healthcare and public health policies will be covered in theory. Students will develop decision-making skills based on evidence .

1. Critically appraise literature and apply evidence-based knowledge for the appropriate , effective, safe use of medicines and provision of individualised care
2. Discuss the development of evidence-based guidelines, hierarchy of evidence and the translation of evidence-based knowledge to clinical practice
3. Interpret and appraise qualitative and quantitative research studies and discuss ethical research principles
4. Understand the principles and practice of pharmacoepidemiologic analysis to inform evidence-based practice and public health policy
5. Describe the design, methodologies and interpretation of pharmacoepidemiologic studies and qualitative research
6. Explain the importance of pharmacoeconomic modelling and health economics for the development of evidence-based healthcare practice and public health policy
7. Apply the principles of evidence-based practice to support medicines optimisation and the clinical management of particular patient groups
8. Discuss evidence-based health screening and the use of screening tools, their benefits, risks and limitations in clinical practice
9. Present and communicate evidence-based research to others for the purposes of person-centred care and best practice

The aim of this module is t o provide the student with insight into pharmaceutical care in complex patients and conditions. This module will cover the role of the pharmacist in advanced and complex situations such as palliative care, intensive care, complex medical needs with updates in cancer management, orphan drugs and digital health

1. Describe the pathophysiology, aetiology, epidemiology and clinical management of less frequent cancer types. Outline the most common drug classes, their physicochemical properties, clinical pharmacology, efficacy and side-effects
2. Demonstrate knowledge of the management of cancers in more complex patients, advanced and metastatic cancers. Discuss new and emerging therapies
3. Understand the role of the pharmacist in palliative care and the multidisciplinary collaborative approach to providing person-centred end-of-care treatment
4. Outline the different classes of drugs typically used in intensive care medicine, their mechanism of actions, formulation and delivery, cautions and interactions
5. Discuss recently approved orphan drugs in relation to evidence-based studies, efficacy, cost and implications for the practice of pharmacy
6. Devise pharmaceutical care plans for patients with more complex medical needs and at an organisational level
7. Recognise the importance of and apply the use of recent digital technologies and medical devices for enhanced patient care

This module will provide students with the opportunity to critically appraise and discuss contemporary challenges faced by pharmacy practice and healthcare . Topical subjects will be covered such as globalisation, environmental sustainability and digital health. Students will further develop their skills in literature review and understand ing of public and government policies.

1. Assess the impact of the ageing population and age-related disease on global health, pharmacy and the pharmaceutical industry
2. Critique the challenges faced by globalisation, changing demographics, control of infection and environmental sustainability on health, pharmaceutical development of new drugs and the practice of pharmacy
3. Discuss ongoing health inequalities and current health of the national and global population
4. Evalu at e the impact of medicines shortages, availability and supply chain issues in Ireland and globally and devise plans to limit negative consequences to patient care
5. Appraise rising drug prices, drug shortages and availability of affordable drugs in relation to drug development, the patient and pharmacy practice
6. Discuss the challenges faced by digital health and patient confidentiality, data security and legislation compliance
7. Demonstrate awareness of and propose possible strategies to reduce the environmental impact of medicines use, healthcare and pharmacy practice and take action to improve sustainability
8. Discuss emerging challenges affecting healthcare, medicines use and pharmacy practice

The aim of this module is t o update the student on novel advancements in drug development, pharmaceutical processing with updates in recent drug approvals and digital technologies and any regulatory guidelines. This module will ensure the student enters practice with up-to-date knowledge of cutting-edge pharmaceutical sciences and novel drugs entering the market

1. Demonstrate basic awareness of advanced and emerging techniques used for the discovery and design of new drugs
2. Describe the current and future methods used for testing small and large new drug entities as required by the regulatory authorities
3. Discuss advancements in pharmaceutical formulation, manufacturing processes and design of drug delivery systems
4. Outline recently approved therapies and examples of drugs in late development stage for diseases with unmet clinical need and show awareness of their medicinal chemistry and clinical pharmacology
5. Critically evaluate advancements in personalised/stratified medicines, digital health and technology innovations relevant to healthcare and pharmacy
6. Discuss regulatory updates relevant to the approval of new drugs, medical devices and digital technology

The purpose of this module is to prepare the student for practice. The key topics of pharmacy practice will be revisited and expanded further with any relevant updates. These topics will include clinical pharmacy skills, professionalism , legislation, medicines safety, health policies, health promotion and roles and responsibilities of the pharmacist. Reflective practice, PSI competenc y requirements and OSCE preparation will be integrated throughout this module .

1. Critically discuss the current and future roles and responsibilities of pharmacists and the input of the pharmacy profession as a whole in healthcare service provision
2. Apply knowledge of health policies in Ireland applicable to pharmacy practice and discuss the influence pharmacy practice has on policy development for the improvement of public health
3. Critically evaluate the importance, development and application of risk management systems and the role of pharmacy in medicines safety, pharmacovigilance and response to adverse drug reactions
4. Integrate clinical therapeutics and apply evidence-based knowledge for the provision of patient-centred care and effective and safe medicines use
5. Competently respond to symptoms, conduct basic clinical examinations and patient consultations, communicate effectively with patients and professionals, perform pharmaceutical interventions and medicines use reviews and develop pharmaceutical care plans
6. Use behavioural sciences knowledge and interventional skills to support behavioural change, medicines adherence and concordance and the promotion of healthy living
7. Reflect on the importance of continued quality improvement of pharmacy services and periodic review using timely and appropriate auditing tools
8. Apply professional and ethical judgement, make informed decisions and critically reflect on fitness to practice
9. Critically reflect on self-knowledge and show commitment to continuing professional development and lifelong learning and development
10. Practice pharmacy skills and complete OSCE stations

This module will provide students with the opportunity to gain research skills in a topic related to pharmacy practice. The project will develop further skills in formulating a research question, planning a research methodology , qualitative research techniques, problem solving, collection and analysis of data, critical evaluation of findings, project management and academic writing and presentation.

1. Understand and contribute to the design of a research question and project proposal
2. Plan an appropriate methodological approach to address the research question and devise a project schedule for successful project management
3. Apply problem-solving and critical appraisal skills to literature searching and data acquisition
4.
Methodologically collect, analyse, interpret and appropriately present data

5. Compile research findings and present the independent research in the form of a written dissertation/publication and oral presentation
6. Utilise self-study skills, time management skills and presentation skills
7. Work collaboratively with others

This module will allow the student to consolidate professional practice and public health skills and learning. The module will be delivered online as directed learning, and it will be managed aligned to the APPEL structures (Affiliation for Pharmacy Practice Experiential Learning), in common with other MPharm programmes. This module will be undertaken while on eight months of work placement (30 hr per week) and the student will have the opportunity to build on their professional practice skills. 100 % attendance is required for practice placement. Developing competence in all Domains (1 to 5) of the Core Competency Framework (CCF) for Pharmacists will be required during this practice placement. This module aims to help students develop their knowledge, skills and attributes in CCF Domain 1, Professional practice and Domain 5, Public Health

1. Act and practice according to the expectations of a professional pharmacist in line with legislation and the relevant codes of conduct
2. Demonstrate commitment to personal and professional reflective practice and continuous personal and professional development
3. Apply critical appraisal skills, evidence-based research, clinical reasoning and decision-making skills to practice according to national and international policies and guidelines
4. Discuss current and future global public health burdens, interests, challenges and barriers in the context of pharmacy practice
5. Discuss the availability of health screening in the context of ethics, pharmacoeconomics and evidence
6. Demonstrate the knowledge, professionalism, skills and responsibility to be patient-focused in practice

This module will allow the student to consolidate their knowledge of the supply and distribution of medicines. . The module will be delivered online as directed learning, and it will be managed aligned to the APPEL structures (Affiliation for Pharmacy Practice Experiential Learning), in common with other MPharm programmes. This module will be undertaken while on eight months of work placement (30 h per week) where the student will have the opportunity to use their knowledge of supply and disruption of medicines in practice. 100 % attendance is required for practice placement. The goal of the practice placement is to ensure students develop and can demonstrate competency in all core behaviours outlined in the Pharmaceutical Society of Ireland Core Competency Framework (CCF) Domains 1-5.

The module aims to facilitate the demonstration of the competencies required of a practitioner working in a patient-facing role as related to the Supply of Medicines and organisation and Management Skills.

1. Describe supply chain networks and management in the practice of pharmacy
2. Understand the importance of supply chain management and good distribution practice (GDP) for maintaining quality and safety of medicines supply and patient use
3. Develop and utilise risk management and quality assurance processes
4. Apply the basics of pharmacy financial management, use procurement systems and pharmacoeconomic modelling to justify and manage the medicines supply chain
5. Communicate and educate patients on storage and use of medicines to maintain quality and for safe and effective use
6. Adapt to change in supply system management processes

This module will develop skills in the Safe, Responsible and Ethical Use of Medicines, with particular emphasis on ensuring the safe use of medicines and actively implementing risk minimisation practices.

This Module will be undertaken while on eight months of work placement. The work placement will amount to 30 hours per week.

100 % attendance is required for practice placement

The module will be delivered online as directed learning, and it will be managed aligned to the APPEL structures (Affiliation for Pharmacy Practice Experiential Learning), in common with other MPharm programmes.

This module aims to support students in developing the behaviours outlined in the PSI CCF Domain 2, Personal Skills and Domain 4, Safe and Rational use of Medicines. It will help students to develop and demonstrate personal skills, including decision – making and leadership skills, which are identified by the PSI as fundamental but challenging skills to achieve.

The goal is to ensure students develop and can demonstrate competency in all core behaviours outlined in the Pharmaceutical Society of Ireland Core Competency Framework (CCF) Domains 1-5 during the practice placement.

The Professional Registration Examination (PRE) is undertaken at the end of this module, in September. This is a legal requirement and the PRE must be undertaken to complete the MPharm programme. This is a pass or fail module and exam. Students passing this exam and module are eligible to apply to be registered as a pharmacist.

1. Act as a responsible and professional lead in ensuring the safe use of medicines and actively implement risk minimisation practices
2. Compose and provide reliable, accurate evidence-based information on medicines use and communicate this effectively to patients, healthcare professionals and the wider public
3. Evaluate the rational and safe use of medicines in patients and show leadership in ethical, responsible and rational use of medicines in accordance with evidence-based practice
4. Develop and follow pharmaceutical care plans and collaborate to ensure safe continuity of patient care and medicines use
5. Prove commitment to continuing professional development and reflective practice in all aspects of pharmacy