This module aims to provide the student with a fundamental understanding of both the theory and practical aspects of protein purification processing as it pertains to the manufacture of modern biopharmaceutical products.

This course in NIBRT is designed to deliver an introduction to the typical downstream operations used in a biopharmaceutical production process. This course includes both hands-on practical and lecture components covering topics such as harvest, ultrafiltration/diafiltration, viral clearance and chromatography.

During this course, trainees will be introduced to the basics of filtration and chromatography in a theory session before building on this knowledge and performing these operations using a practical component.

On completion of this course at NIBRT (or an affiliated NIBRT Global Partner site) earn your NIBRT Global Qualification by completing this micro-credential.

NIBRT Global Qualification (NGQ)

The NIBRT Global Qualifications (NGQs) are internationally recognised training qualifications setting a new benchmark for biopharmaceutical education and workforce development.

Earn your NGQ by completing a micro-credential accredited by ATU – a short, flexible and accredited way to upskill and advance your biopharma career.

Learning Outcomes

• Outline the main stages of downstream processing for biologics.
• Describe the main harvesting techniques used for purification of a biologic.
• Explain the basic theory and practice of column chromatography for biologic purification operations.
• Outline the theory and practice of ultrafiltration and diafiltration operations for biologics.